#Drug-design

Showing 16 of 16 repositories tagged #drug-design, ranked by stars

AspirinCode
AspirinCode
papers-for-molecular-design-using-DL

List of Molecular and Material design using Generative AI and Deep Learning

Score
90
★ 945 ⑂ 120
MolecularAI
MolecularAI
REINVENT4

AI molecular design tool for de novo design, scaffold hopping, R-group replacement, linker design and molecule optimization.

Score
100
★ 813 ⑂ 221 +4/day
Python
Mariewelt
Mariewelt
OpenChem

OpenChem: Deep Learning toolkit for Computational Chemistry and Drug Design Research

Score
100
★ 750 ⑂ 120 +3/day
Python
arneschneuing
arneschneuing
DiffSBDD

A Euclidean diffusion model for structure-based drug design.

Score
75
★ 516 ⑂ 126
Python
EDAPINENUT
EDAPINENUT
CBGBench

Official code repository of < CBGBench: Fill in the Blank of Protein-Molecule Complex Binding Graph >

Score
60
★ 328 ⑂ 38
Python
MorganCThomas
MorganCThomas
MolScore

An automated scoring function to facilitate and standardize the evaluation of goal-directed generative models for de novo molecular design

Score
80
★ 243 ⑂ 35
Python
jssweller
jssweller
DrugHIVE

DrugHIVE: Structure-based drug design with a deep hierarchical generative model

Score
40
★ 115 ⑂ 16
Python
chao1224
chao1224
ProteinDT

A Text-guided Protein Design Framework, Nat Mach Intell 2025 (https://www.nature.com/articles/s42256-025-01011-z)

Score
30
★ 107 ⑂ 10
Python
AstraZeneca
AstraZeneca
awesome-drug-pair-scoring

Readings for "A Unified View of Relational Deep Learning for Drug Pair Scoring." (IJCAI 2022)

Score
50
★ 99 ⑂ 15
asarigun
asarigun
awesome-denovo-papers

Awesome De novo drugs design papers

Score
25
★ 94 ⑂ 14
coleygroup
coleygroup
shepherd

Training and inference code for ShEPhERD: Diffusing shape, electrostatics, and pharmacophores for bioisosteric drug design [ICLR 2025 oral]

Score
70
★ 93 ⑂ 12
Python
EDAPINENUT
EDAPINENUT
ppflow

This repository is the official code source of PPFlow: Target-Aware Peptide Design with Torsional Flow Matching (ICML2024)

Score
20
★ 92 ⑂ 12
Python
lucidrains
lucidrains
neural-plexer-pytorch

Implementation of Nvidia's NeuralPlexer, for end-to-end differentiable design of functional small-molecules and ligand-binding proteins, in Pytorch

Score
0
★ 52 ⑂ 3
Python
mahsasheikh
mahsasheikh
DrugGen

DrugGen: Advancing Drug Discovery with Large Language Models and Reinforcement Learning Feedback

Score
0
★ 21 ⑂ 3
Python
Hassantaha999
Hassantaha999
reinvent-UI

An interactive web-based UI app for REINVENT that enables users to generate input files for running REINVENT calculations.

Score
10
★ 20 ⑂ 9
Python
pregHosh
pregHosh
MolCraftDiffusion

A generative AI framework for 3D molecular generation and data-driven molecular design in computational chemistry.

Score
50
★ 16 ⑂ 3
Python
Related Topics
#generative-ai#drug-discovery#deep-learning#machine-learning#generative-model#cheminformatics#chemistry#reinforcement-learning#ai#denovo-design#molecule-generation#deep-generative-models

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